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Non-psychoactive cannabis compound cannabidiol (CBD) has a range of therapeutic possibilities, and is set to be at the center of marijuana research over the next few years. But could non-intoxicating CBD wholesale products, such as vape juices, tincture oils, creams and more also help to treat allergies?

What are allergies?

An allergy is when the body is adversely affected by a certain food or substance, such as kiwis or pollen. Some people are allergic to nuts, medication or even household detergents.

According to the John Hopkins University, allergic reactions affect more than 50 million people living in the United States, making them the sixth-most common chronic illness. Children are especially affected by allergies, but adults can also become allergic to substances they were never previously bothered by.

Allergic reactions are usually just a nuisance, however in some cases they can be more severe.

What happens during an allergic reaction?

The allergic reaction typically occurs just a few minutes after a person is exposed to the troublesome substance. This can lead to a runny or blocked nose, sneezing or coughing. Many people break out in a rash, and those with asthma, eczema or other skin conditions often find that their symptoms get worse.

The body responds in this way to an allergen due to the immune system becoming overactive, and triggering needless inflammation. The immune system generates an antibody known as Immunoglobin E. CBD is an intriguing potential treatment for allergies, because of its unique anti-inflammatory properties and close relationship with the immune system.

 Can CBD help with allergies?

Cannabinoids, or phytocannabinoids, from hemp and cannabis work primarily in the body’s endocannabinoid system (ECS), which contains two main types of cannabinoid receptor. The CB2 receptor provides the critical, and previously unknown link between the ECS and the immune system. When endocannabinoids such as anandamide and 2-Arachidonoylgycerol (2-AG), which are synthesized by the body, bind with CB2 receptors, anti-inflammatory and immunomodulatory messages are sent to the immune system, thereby regulating inflammation.

CBD is not a CB2 receptor agonist, and nor does it stimulate the production of endocannabinoids. However, the cannabinoid does block the degradation of anandamide, seemingly by stopping it from being transported to an enzyme called fatty acid amide hydrolase (FAAH). By acting as a direct or indirect FAAH inhibitor, CBD increases concentrations of anandamide in the body, making more of it available to connect with CB2 receptors and moderate inflammatory responses. Endocannabinoids work to suppress the release of proteins known as cytokines, which have an inflammatory effect.

The immune system is notoriously sensitive, but CBD’s value as an ECS regulator means it’s also an effective therapeutic agent there, as well. Ensuring that endocannabinoid levels in the body remain high helps to prevent an unbalanced immune system response, and protect from allergic reactions.

CBD also has potent anti-nausea properties, which could be helpful in treating an allergic reaction. On rare occasions, allergies can cause pain and headaches, which CBD could be used to relieve thanks to its analgesic effects.

If an allergy has caused a rash or worsened a skin complaint, then an infused topical product may be applied to calm the skin. CBD can have an anti-inflammatory effect on the skin, and also boasts antifungal, antimicrobial and antibacterial qualities.

Can you be allergic to CBD?

CBD – and cannabis in general – may have a long list of medicinal benefits, but it’s important to note that it doesn’t work for everybody. Some people are allergic to cannabis and since legalization, there has been an increase in reported allergic reactions to cannabis, which have been linked to irregular mood, upper respiratory symptoms and irritated skin.

Since many wholesale CBD products are full-spectrum, and are therefore made from an entire hemp plant extract, it is feasible that these could cause allergic reactions. Indeed, part of the reason that cannabis allergies are so rare could be because of restricted access due to prohibition. If full-spectrum CBD has proven problematic, switching to a CBD-isolate product may yield better results, as these separate the CBD from the rest of the extract.

Final thoughts

CBD appears to offer multiple benefits for people with allergies, by helping to reduce inflammation and manage sensitive immune systems, while offering relief from symptoms such as nausea and chronic pain. Ideally, a clinical study will be conducted in the near future looking specifically at the benefits of CBD for allergies, particularly since we are aware that the cannabinoid has an unusual buy powerful impact on the immune system.